|
Symbol Name ID |
Pdyn
prodynorphin MGI:97535 |
| Darker colors indicate more annotations |
| Human Phenotypes | CNS demyelination |
Agenesis of corpus callosum |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Dysmetria |
Gait ataxia |
Limb ataxia |
Tremor |
Babinski sign |
Dysarthria |
Addictive alcohol use |
Hyperreflexia |
Polyneuropathy |
Sensorimotor neuropathy |
Impaired distal proprioception |
Impaired vibration sensation in the lower limbs |
| Disease(s) Associated with PDYN | ||||||||||||||||
| alcohol dependence | ||||||||||||||||
| spinocerebellar ataxia type 23 |
| Mouse Phenotypes | increased susceptibility to pharmacologically induced seizures |
abnormal brain interneuron morphology |
abnormal cerebellar granule cell morphology |
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| Availability | Mouse Genotype | |||
| Pdyntm1(cre)Czer/Pdyntm1(cre)Czer | ||||
| Pdyntm1(cre)Czer/Pdyn+ | ||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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